The Glor lab is hosting this month’s TGIF. Come join us on the patio this Friday 17th May at 4pm for beer and dim sum!
Monday, April 29, 2013
Our senior undergraduate, Ben Desch, will be presenting his Honours thesis “Phylogeography and population structure of the Anolis chlorocyanus species group” this Wednesday at 2:30pm in Hylan 305. Everyone is welcome, so come and support Ben to hear the exciting results from his work in the lab this last year!
Sunday, April 28, 2013
We’re going to change directions a bit and talk about some QTL studies of Heliconius.
Baxter, S. W., S. E. Johnston and C. D. Jiggins 2009. Butterfly speciation and the distribution of gene effect sizes fixed during adaptation. Heredity 102(1): 57-65 [doi]
Papa, R., D. D. Kapan, B. A. Counterman, K. Maldonado, D. P. Lindstrom, R. D. Reed, H. F. Nijhout, T. Hrbek and W. O. McMillan 2013. Multi-Allelic Major Effect Genes Interact with Minor Effect QTLs to Control Adaptive Color Pattern Variation in Heliconius erato. Plos One 8(3) [doi]
Sunday, April 21, 2013
Lab meeting discussions this semester have moved from mice to flycatchers to sticklebacks. Guiggy and I are going to end the semester with a bang with papers on Heliconius butterflies this week and the next. For this week, we’ll be discussing the following two papers:
Dasmahapatra KK et al. 2012 Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. Nature 487: 94–98 [doi]
Brower, A. V. Z. 2013. Introgression of wing pattern alleles and speciation via homoploid hybridization in Heliconius butterflies: a review of evidence from the genome. Proceedings of the Royal Society B: Biological Sciences 280 [doi]
Monday, April 15, 2013
We’re going to be changing it up for this week’s lab meeting. This week, I would like some feedback on a manuscript which is also the last chapter of my thesis (whoop!). It is still a work in progress so while any feedback is welcome, I’d really like suggestions about the direction of the paper.
Wednesday, April 10, 2013
Our paper reporting new adenovirus strains in collaboration with two veterinarians came out today. Check it out!
Tuesday, March 26, 2013
We’re going to switch topics to sticklebacks for the next 3 weeks, and there’s plenty to talk about. I’d like to begin with consideration of research exploring the genetic architecture of ecomorph traits in sticklebacks, and how these studies contribute to resolving outstanding, largely theoretical debates about the the nature of adaptive evolution. So we’ll read the following three empirical papers and discuss how they relate to the genetics of adaptation addressed in two previous reviews. This is a complex subject to examine, so I expect we’ll spend the first two weeks on this.
Colosimo, P. F., C. L. Peichel, K. Nereng, B. K. Blackman, M. D. Shapiro, D. Schluter, and D. M. Kingsley. 2004. The genetic architecture of parallel armor plate reduction in threespine sticklebacks. PLoS Biology 2:E109.
Jones, F. C., M. G. Grabherr, Y. F. Chan, P. Russell, E. Mauceli, J. Johnson, R. Swofford, M. Pirun, M. C. Zody, S. White, E. Birney, S. Searle, J. Schmutz, J. Grimwood, M. C. Dickson, R. M. Myers, C. T. Miller, B. R. Summers, A. K. Knecht, S. D. Brady, H. Zhang, A. A. Pollen, T. Howes, C. Amemiya, Broad Institute Genome Sequencing Platform & Whole Genome Assembly Team, J. Baldwin, T. Bloom, D. B. Jaffe, R. Nicol, J. Wilkinson, E. S. Lander, F. Di Palma, K. Lindblad-Toh, and D. M. Kingsley. 2012a. The genomic basis of adaptive evolution in threespine sticklebacks. Nature 484:55–61.
Genetics of Adaptation:
Orr, H.A. The genetic theory of adaptation: a brief history. Nature Reviews Genetics 6:119-127
Thursday, March 14, 2013
We will read two data driven papers this week:
Ellegren, H., L. Smeds, R. Burri, P. I. Olason, N. Backström, T. Kawakami, A. Künstner, H. Mäkinen, K. Nadachowska-Brzyska, A. Qvarnström, S. Uebbing, and J. B. W. Wolf. 2012. The genomic landscape of species divergence in Ficedula flycatchers. Nature 491:756–760. [doi link]
Wiley, C., A. Qvarnström, G. Andersson, T. Borge, and G.-P. Saetre. 2009. Postzygotic isolation over multiple generations of hybrid descendents in a natural hybrid zone: how well do single-generation estimates reflect reproductive isolation? Evolution 63:1731–1739. [doi link]
Monday, March 4, 2013
To start our discussion of flycatchers we will read two reviews:
Qvarnström, A., A. M. Rice and H. Ellegren. 2010. Speciation in Ficedula flycatchers. Philosophical Transactions of the Royal Society B: Biological Sciences 365:1841–1852. [doi link]
Qvarnström, A. and R. I. Bailey. 2009. Speciation through evolution of sex-linked genes. Heredity 102:4–15. [doi link]
Tuesday, February 26, 2013
We’re going to conclude our readings on the genomics of speciation in mice by reading papers related to recombination and speciation. The first paper is a recent review by Nachman and Payseur that attempts to disentangle the contributions of reduced gene flow and selection at linked sites to genomic differentiation in regions of low recombination in mice and rabbits. The second study by Payseur and Place scans the genomes of mice for loci experiencing linkage disequilibrium that might be associated with Dobzhansky-Muller incompatibilities. I’m also providing a link to to a predecessor of this second study by Payseur and Hoekstra.
Nachman, M. W., and B. A. Payseur. 2012. Recombination rate variation and speciation: theoretical predictions and empirical results from rabbits and mice. Philosophical Transactions Of The Royal Society B-Biological Sciences 367:409–421. [doi link]
Payseur, B. A., and M. Place. 2007. Searching the genomes of inbred mouse strains for incompatibilities that reproductively isolate their wild relatives. The Journal of heredity 98:115–122. [doi link]
Payseur, B. A., and H. E. Hoekstra. 2005. Signatures of reproductive isolation in patterns of single nucleotide diversity across inbred strains of mice. Genetics 171:1905–1916. [doi link]
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