Lab Meeting 28 March: Sticklebacks and the genetics of adaptation

Posted on Posted in Uncategorized

We’re going to switch topics to sticklebacks for the next 3 weeks, and there’s plenty to talk about. I’d like to begin with consideration of research exploring the genetic architecture of ecomorph traits in sticklebacks, and how these studies contribute to resolving outstanding, largely theoretical debates about the the nature of adaptive evolution. So we’ll read the following three empirical papers and discuss how they relate to the genetics of adaptation addressed in two previous reviews. This is a complex subject to examine, so I expect we’ll spend the first two weeks on this.

Stickleback Papers:
Albert, A. Y. K., S. Sawaya, T. H. Vines, A. K. Knecht, C. T. Miller, B. R. Summers, S. Balabhadra, D. M. Kingsley, and D. Schluter. 2008. The genetics of adaptive shape shift in stickleback: pleiotropy and effect size. Evolution 62:76–85
DOI

Colosimo, P. F., C. L. Peichel, K. Nereng, B. K. Blackman, M. D. Shapiro, D. Schluter, and D. M. Kingsley. 2004. The genetic architecture of parallel armor plate reduction in threespine sticklebacks. PLoS Biology 2:E109.
DOI

Jones, F. C., M. G. Grabherr, Y. F. Chan, P. Russell, E. Mauceli, J. Johnson, R. Swofford, M. Pirun, M. C. Zody, S. White, E. Birney, S. Searle, J. Schmutz, J. Grimwood, M. C. Dickson, R. M. Myers, C. T. Miller, B. R. Summers, A. K. Knecht, S. D. Brady, H. Zhang, A. A. Pollen, T. Howes, C. Amemiya, Broad Institute Genome Sequencing Platform & Whole Genome Assembly Team, J. Baldwin, T. Bloom, D. B. Jaffe, R. Nicol, J. Wilkinson, E. S. Lander, F. Di Palma, K. Lindblad-Toh, and D. M. Kingsley. 2012a. The genomic basis of adaptive evolution in threespine sticklebacks. Nature 484:55–61.
DOI

Genetics of Adaptation:
Hoekstra, H.E., and J.A. Coyne. 2007. The locus of adaptation: evo-devo and the genetics of adaptation. Evolution 61(5):995-1016.
DOI

Orr, H.A. The genetic theory of adaptation: a brief history. Nature Reviews Genetics 6:119-127
DOI